Aweber is one of the best bulk e-mail and autoresponder service providers out there. It is much easier to use than its rivals such as Get Response and Mail Chimp.
You an set up a list in minutes and start building your e-mail (and phone number/address if you want) database right away.
You can send automated e-mails via the autorepsonder service. Deliverability is excellent too
Chck out my blog post and accompanying Aweber tutorial here: